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Molecular Jackhammers Drill Pathway to Killing Cancer Cells   

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Stimulating vibronic modes in cell membranes works by activating aminocyanine molecules (the MJHs), which can easily adhere to the outside of cells due to their positive charge, opposite to the cell’s phospholipid bilayer.

Once attached, MJH is activated by exposing these molecules to invisible infrared light (IR) frequency or energy, slightly lower than the energy of visible red light. Since red radiation has the lowest energy in the visible spectrum, any light below red is invisible, and this band or range of frequencies is called near-infrared (NIR).

When activated with NIR, electrons within the MJH create plasmons — an excitation of the entire molecule that causes vibrations at an extremely fast rate. Driven by the NIR radiation, MJHs hit as if they were continually hammering the cell’s surface. These collective hammer blows of the MJHs are strong enough to rupture or crack the cell’s membrane creating a decompensation sufficient to destroy it.

From the medical point of view, when this technique is available, it will be beneficial and less expensive than methods such as photothermal therapy, photodynamics, radio-radiation and chemotherapy.

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